In this article, you’ll learn:
- Why recent headlines about acetaminophen and pregnancy are causing confusion
- What the American College of Obstetricians and Gynecologists (ACOG) says about Tylenol use
- The difference between association and causation in research
- Why untreated fever can be riskier than the medication itself
- Dr. Lauren Hamilton’s advice for using pain relief safely during pregnancy
Understanding the concerns
Recent headlines have raised questions about the safety of acetaminophen (Tylenol) during pregnancy, suggesting possible risks for developing babies. It’s understandable that many women feel confused or worried.
The American College of Obstetricians and Gynecologists (ACOG), the nation’s leading authority on pregnancy and women’s health representing more than 60,000 doctors, considers acetaminophen a safe and effective choice for treating pain and fever during pregnancy. This guidance comes from decades of careful, evidence-based research.

Dr. Lauren Hamilton, Medical Director of Women, Infants & Children at Roper St. Francis Healthcare
Dr. Lauren Hamilton, Medical Director of Women, Infants & Children at Roper St. Francis Healthcare, says these headlines are concerning because they could lead women to avoid a medication that is often both safe and necessary.
“I worry that fear-based messages can cause women to suffer through pain or fever without treatment,” she says. “Untreated fever can sometimes be far more dangerous than the medication itself.”
Association vs. Causation
Dr. Hamilton says it’s important to understand the difference between association and causation. “Just because two things appear together in a study doesn’t mean one caused the other,” she explains. “In many cases, there are other factors behind the data that tell the real story.”
For example, some studies link acetaminophen to developmental issues, but they often don’t consider why someone used the medication. “A woman may take Tylenol because she has a fever or infection,” Dr. Hamilton says. “Those conditions, not the medication, can pose risks to a developing baby.”
What the research shows
Research on acetaminophen and child development has been inconsistent. Some studies show a slight increase in risk, while others show no link at all or even a decrease. “When you look at the totality of the evidence, acetaminophen continues to be the safest option for pregnant women who need relief from pain or fever,” says Dr. Hamilton.
She also stresses that the scientific process takes time. “Good research is slow, careful, and repeatable,” she explains. “Right now, there’s not enough quality evidence to say that acetaminophen causes harm to babies. What we have are studies that raise questions, and that’s very different from proof.”
Dr. Hamilton’s advice
Dr. Hamilton encourages expectant mothers to stay informed but not alarmed. “Pregnancy already comes with enough uncertainty,” she says. “You deserve clear, science-based information that helps you make the best choices for yourself and your baby.”
She also reminds patients that all medications have some level of risk. “There’s no such thing as a completely risk-free medication,” Dr. Hamilton says. “The goal is to use the safest option at the lowest effective dose for the shortest amount of time, and acetaminophen meets that standard.”
The bottom line
Pregnant women can feel confident following their healthcare provider’s advice about acetaminophen use. While more research is always helpful, current evidence supports its safety when used appropriately.
Dr. Hamilton sums it up simply: “If you’re pregnant and need to treat a fever or pain, acetaminophen is still the safest choice we have. And if you’re ever unsure, talk to your doctor. We’re here to help you navigate these decisions with clarity and compassion.”

